To analyze the clinical management ofthe renal transplant recipient from a kidney living donor.The renal transplantation (RT) from a living donor withoutsurgical complications has a very low frequency ofacute tubular necrosis (ATN) that facilitates enormouslythe clinical control. The scheme of follow-up after-RTmust include: (1) Hemodynamic monitoring; (2) Clinicalmanagement; (3) Renal allograft monitoring: renalfunction, diuresis, radionuclide imaging and ultrasound-Doppler; (4) Pharmacological treatment: analgesia,gastric protection, antibiotic prevention; (5) Monitoringof the immunosuppressive therapy; (6) Digestive monitoring;(7) Control of the cardiovascular risk; (8) Preventionsinfectious; (9) Osteodistrophia control. In living donor RTa rapid normalization of the renal function and a timeof hospitalization reduced are observed. The presenceof a long ATN or a renal dysfunction of the graft mustforce to realize an early renal allograft biopsy.