
A PROPÓSITO DE UN NUEVO CASO DE INFECCIÓN DEL TRACTO URINARIO POR KLEBSIELLA PNEUMONIAE (ST258) PRODUCTOR DE KPC-3 EN ESPAÑA
Antonio Sorlózano-Puerto, David Esteva-Fernández, Jesús Oteo-Iglesias, José María Navarro-Marí, José Gutiérrez-Fernández
A PROPÓSITO DE UN NUEVO CASO DE INFECCIÓN DEL TRACTO URINARIO POR KLEBSIELLA PNEUMONIAE (ST258) PRODUCTOR DE KPC-3 EN ESPAÑA
OBJECTIVE: We describe the characterization of a new isolated in Spain of Klebsiella pneumoniae ST258 producing KPC-3, carbapenems non-susceptible, recovered from a sample of urine from a patient with urinary tract infection and no history of carbapenems exposure.METHODS: After the isolation, identification of K. pneumoniae was performed by biochemical tests and mass spectrometry. The carbapenems susceptibility testing was performed by microdilution and E-test in cation-adjusted Mueller-Hinton. The study was completed by Rapidec® Carba NP. In order to determine the genetic basis of resistance to carbapenems we used Xpert® Carba-R for carbapenemase type and subtype was subsequently analyzed by amplification by PCR and sequencing. RESULT: We demonstrated by MLST that the strain belonged to the clone of high-risk ST258. CONCLUSIONS: This is the first characterization, in our media, of a clinical isolated of K. pneumoniae ST258 producing KPC-3 and no history of carbapenems exposure.
Klebsiella pneumoniae / Carbapenemase / ST258 {{custom_keyword}} /
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