TRATAMIENTO DEL CÁNCER DE VEJIGA NO MÚSCULO INFILTRANTE REFRACTARIO AL BACILO CALMETTE-GUÉRIN

Polat Turker, Levent Turkeri

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Archivos Españoles de Urología ›› 2013, Vol. 66 ›› Issue (9) : 833-840.
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TRATAMIENTO DEL CÁNCER DE VEJIGA NO MÚSCULO INFILTRANTE REFRACTARIO AL BACILO CALMETTE-GUÉRIN

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Abstract

Treatment options for patients with nonmuscle invasive bladder cancer (NMIBC) refractory to intravesical bacillus Calmette-Guérin (BCG) therapy is reviewed in this article based on the recent published literature. Although intravesical BCG is the best bladder sparing treatment option for NMIBC to prevent recurrence and progression, about 1/3 of cases are refractory to this treatment. At this point radical cystectomy is the standard treatment of choice. If this option is not feasible, intravesical chemotherapy with docetaxel or gemcitabine, the combination of BCG and interferon (INF)-α or device-assisted intravesical strategies, such as mitomycin-EMDA or chemohyperthermia are some of the candidates for further treatment.

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Non-muscle invasive bladder cancer / BCG failure / Itravesical therapy

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Polat Turker , Levent Turkeri. TRATAMIENTO DEL CÁNCER DE VEJIGA NO MÚSCULO INFILTRANTE REFRACTARIO AL BACILO CALMETTE-GUÉRIN. Archivos Españoles de Urología. 2013, 66(9): 833-840

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