Publication of a scientific work is the finaland obligatory stage of any research. Among the variousexisting types of medical publications, the research originalarticle is the prototype of scientific article. Its finalityis to communicate the investigation undertaken to thereader in a coherent, clear and precise manner. With thatpurpose, the discoveries found by the authors as an answerto a hypothesis are presented and discussed.To send the original article to a biomedical journal, themanuscript should present some adequate formalcharacteristics, in addition to contain scientifically validinformation. That can be achieved by complying with therules past by the International Committee of BiomedicalJournal Editors which have been adopted by a greatnumber of scientific journals as publication requisites.The objective of this article is to describe the structureof the various parts (first page, abstract, introduction,material and methods, results, discussion, andbibliographic references) that constitute the format of theresearch original article, exposing the main adverse to beavoided during its preparation.