OBJECTIVES: To report an exceptional case ofmulticystic mesothelioma of the testicular tunica vaginalis.METHODS: A 72-year-old male was referred for study of ascrotal mass. Physical examination, blood tests, and ultrasoundwere performed prior to surgical excision and pathologic study of thelesion.RESULTS: The ultrasound study showed a multilobar cysticlesion near the spermatic cord. Pathology reported multiple 3-4 mmcystic formations, with rudimentary papillae covered by ahyperchromatic epithelium and vimentin (+), CD 34 (+)immunophenotype.CONCLUSIONS: Multicystic mesothelioma is a rare form ofmesothelioma, easy to recognize but infrequent. This tumor generallyaffects the peritoneal surface of the pelvis and abdomen; althoughother less frequent locations have been described testicular locationis exceptional. We report the case of a patient presenting with amulticystic mesothelioma of the testicular tunica vaginalis andreview the diagnosis, pathology and treatment options for this typeof tumor.