Carcinoma urotelial primario de uretra bulbomembranosa. Estudio histolÛgico e inmunohistoquÌmico de un caso

DAVID PARADAD, ALBERTO PÁEZ, MARISELA ACOSTA, LUIS CARICOTE, EDUARDO TRUJILLO, JUAN CARLOS LUIGI, ROSA M. FARÕAS C

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Archivos Españoles de Urología ›› 2003, Vol. 56 ›› Issue (10) : 1144-1147.
Case Report

Carcinoma urotelial primario de uretra bulbomembranosa. Estudio histolÛgico e inmunohistoquÌmico de un caso

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Abstract

OBJECTIVE:We report acase of a primary urothelialcarcinoma of the bulbomembranous urethra, with special emphasison histopathological and immunohistochemical findings.METHODS/RESULTS: A 63-year-old man presented urethralobstruction symptoms. A radical phalectomy was performed and a4.5 x 4 cm bulbomembranous urethral tumor was observed.Histopathological analysis disclosed an urothelial carcinoma, thatshowed positive immunostaining for cytokeratin AE1/AE3,cytokeratin 7, carcinoembrionic antigen and epithelial membraneantigen. The patient recived radiotherapy and adjuvant chemotherapyand is currently free of disease.CONCLUSION: Posterior male urothelial carcinoma of theurethra is a rare neoplasm that usually is mistaken clinically for abenign lesion. The diagnostic is generally made in advanced stageswith a poor therapeutical response.

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Neoplasm / Urethra / Carcinoma / Male / Urothelial / Immunohistochemestry

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DAVID PARADAD , ALBERTO PÁEZ , MARISELA ACOSTA , LUIS CARICOTE , EDUARDO TRUJILLO , JUAN CARLOS LUIGI , ROSA M. FARÕAS C. Carcinoma urotelial primario de uretra bulbomembranosa. Estudio histolÛgico e inmunohistoquÌmico de un caso. Archivos Españoles de Urología. 2003, 56(10): 1144-1147

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