OBJECTIVES: To test the concordancebetween clinical and neurophysiologic data of the varioustypes of erectile dysfunction, and to describe a diagnosticalgorithm based on corpus cavernosum electromyography(cc-EMG).METHODS: 32 patients with a mean age of 50.6 years(typical deviation 13.2 years) referred with the diagnosisof erectile dysfunction underwent medical history,neuroandrologic physical exam, neurophysiologic studies period, threshold and latency of pudendal nervesomatosensory potentials, as well as genital sympatheticevoked potentials-SSR-), and corpus cavernosumelectromyography(cc-EMG) both in basal conditions andafter administration of 20 micrograms of E-1 prostaglandin(PGE-1).RESULTS: 1- A significative relationship was shownbetween clinical data of arterial or corpus cavernosumintrinsic origin erectile dysfunction and patients withvascular or structural lesion on cc-EMG data. 2- Asignificative relationship was shown between patientswithout previous pathologic history and patients withnormal or anxiety cc-EMG. 3- No significative relationshipwas shown between patients with neurologic lesion andpatients with autonomic lesion on cc-EMG. 4- Nosignificative relationship was found between patients withperipheric neurologic lesion and patients with inferiorautonomic lesion on cc-EMG. 5- A significative relationshipwas shown between patients with suprasacral neurologiclesion and patients with superior autonomical lesion oncc-EMG.CONCLUSIONS: Isolated application of pudendal nerveneurophysiologic techniques for the diagnosis of erectiledysfunction is not enough. Autonomic innervation studiesshould be included, with a cc-EMG dichotomic qualitativeinterpretation.