OBJECTIVE: To achieve an effective, safeand fast hemostasis. To translate it into a great diminutionof operating time, avoiding multiple ligatures that aretime consuming and being merely a mechanical, repetitiveact do not add any element of quality to surgery in generaland to urologic pelvic procedures in particular.METHODS: A new hemostatic system has beenexperimented in pelvic urologic open surgery, specificallyin radical cystectomy (RC) (with orthotopic substitutionor urinary diversion) and radical prostatectomy (RP). Itachieves vascular sealing by means of tissue collagenprecipitation when applied in previously dissected vascularpedicles during radical cystectomy and neuro-vascularbundles during radical prostatectomy.RESULTS: It has been noted a complete efficacy in thecoagulation of all vascular pedicles as well as a significantdecrease in operating time (around 25%) because the useof ligatures is completely avoided. It has also been noteda great decrease in blood loss, with reductions in transfusionneeds down to 50% of the cases.CONCLUSIONS: The new hemostatic system by tissuecollagen coagulation allows a fast, effective and safe hemostasis in complex urological pelvic surgery, whichtranslates into operative time savings and minimal bloodloss.