OBJECTIVES: To report the series of our Urology Department in the treatment of urinary stone disease with extracorporeal lithotripsy as well as the effec- tiveness of the Dornier lithotripter MFL-5000. METHODS: 6.602 patients were treated by extracorpo- real lithotripsy during 12 years with a total of 17.120 sessions. We examined the treatment outcome of 4.402 patients with a solitary stone, accordingly to stone size and localization. RESULTS: There were no major complications and only 43 patients experienced “calle litiásica”. We treated 4.402 stones. For all stones, independently of size and localization, 2615 (59.4%) were treated in one session, 801 (18.2%) required two sessions, 379 (8.6%) 3 sessions, 213 (4.8%) 4 sessions and 373 (8.4%) 5 or more sessions. CONCLUSION: The Dornier MFL-5000 lithotripter succe- ssfully treated urinary stone disease in patients of all age groups with a retreatment rate and number of sessions per stone similar to other studies, without analgesia or anesthetic procedures, except in the younger age group.