OBJECTIVES: Due to the fact that melanomaof the penis is rare, we perform a bibliographic reviewabout the subject and analyze the diagnostic criteria,clinical stages and therapeutic options.METHODS: We report one case that was diagnosed andtreated in our department.RESULTS: 85-year-old male who presented with hematuriaand a red brownish irregular elevated lesion in the glanspenis. Partial penectomy was performed.CONCLUSIONS: Melanoma of the penis is a rare tumoralentity. It accounts for about 1% of all penile malignantpathologies. It has bad prognosis due to fast metastasicdissemination (regional lymph nodes and other organs)and delayed diagnosis. First choice treatment is partialpenectomy with or without bilateral inguinal lymphadenectomy(depending upon degree of tumor invasiveness). In caseswith metastasis treatment is palliative with chemotherapyand immunotherapy.